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Evidence Summary
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Got It, Hide thisIn people with rheumatoid arthritis, aerobic exercises and/or strength training improve some symptoms
Hu H, Xu A, Gao C, et al. The effect of physical exercise on rheumatoid arthritis: An overview of systematic reviews and meta-analysis. J Adv Nurs. 2021;77:506-22.
Review questions
In people who have rheumatoid arthritis, do different types of exercise improve symptoms?
Background
Rheumatoid arthritis is a chronic condition. It can cause inflammation, pain, stiffness, and fatigue. It can also cause deformity of the small joints, usually in the hands and feet.
There is no cure for rheumatoid arthritis, but its symptoms can sometimes be controlled. It is uncertain whether exercise can help control the symptoms of rheumatoid arthritis.
How the review was done
The researchers did a systematic review, searching for reviews that were published in English up to September 2019. They found 10 systematic reviews that included 97 individual studies and 7,190 people.
The key features of the studies were:
- people were adults with rheumatoid arthritis;
- types of exercise included aerobic exercise, strength training, aerobic exercise with strength training, aquatic exercise, and hand exercise; and
- specific types of exercise were compared with other exercise, mobility exercise, usual care, or wait list.
What the researchers found
Compared with other exercise or physical activity, mobility exercise, usual care, or wait list:
- aerobic exercise improved aerobic capacity (a measure of how efficiently your body uses oxygen during maximum-intensity exercise) by a large amount;
- strength training improved pain and erythrocyte sedimentation rate (a blood test that indicates the presence of inflammation) by moderate amounts and improved 50-foot walking time by a small amount; and
- aerobic exercise with strength training improved physical function and fatigue by small amounts.
Conclusion
In people with rheumatoid arthritis, aerobic exercise and/or strength training may improve some symptoms.
Effects of exercise in people with rheumatoid arthritis*
| Type of exercise | Outcomes | Number of studies (number of people) | Effect† of exercise program | Quality of evidence |
| Aerobic exercise | Aerobic capacity (a measure of how efficiently your body uses oxygen during maximum-intensity exercise) | 6 studies (282 people) | Large improvement | Very low |
| Strength training | Pain | 3 studies (119 people) | Moderate improvement | Very low |
| Strength training | Erythrocyte sedimentation rate (a blood test that indicates the presence of inflammation) | 2 studies (101 people) | Moderate improvement | Very low |
| Strength training | 50-foot walking time | 2 studies (50 people) | Large improvement | Very low |
| Aerobic exercise with strength training | Physical function | 4 studies (399 people) | Small improvement | Moderate |
| Aerobic exercise with strength training | Fatigue | 4 studies (455 people) | Small improvement | Low |
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Glossary
A comprehensive evaluation of the available research evidence on a particular topic.
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